BDBM50308984 AdoCys::CHEMBL597532::S-Adenosylhomocysteine
SMILES N[C@H](CCSC[C@@H]1O[C@@H]([C@@H](O)[C@H]1O)n1cnc2c(N)ncnc12)C(O)=O
InChI Key InChIKey=ZJUKTBDSGOFHSH-NPLZWRLCSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50308984
Affinity DataKd: 700nMpH: 7.5 T: 2°CAssay Description:For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...More data for this Ligand-Target Pair
Affinity DataKd: 1.10E+3nMpH: 7.5 T: 2°CAssay Description:For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...More data for this Ligand-Target Pair
Affinity DataKd: 1.60E+3nMpH: 7.5 T: 2°CAssay Description:For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...More data for this Ligand-Target Pair
Affinity DataKd: 2.50E+3nMpH: 7.5 T: 2°CAssay Description:For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...More data for this Ligand-Target Pair
Affinity DataKd: 2.90E+3nMpH: 7.5 T: 2°CAssay Description:For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...More data for this Ligand-Target Pair
Affinity DataKd: 2.20E+3nMpH: 7.5 T: 2°CAssay Description:For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...More data for this Ligand-Target Pair
Affinity DataKd: 1.30E+3nMpH: 7.5 T: 2°CAssay Description:For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...More data for this Ligand-Target Pair
Affinity DataKd: 900nMpH: 7.5 T: 2°CAssay Description:For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...More data for this Ligand-Target Pair
Affinity DataKd: 800nMpH: 7.5 T: 2°CAssay Description:For standard ITC analysis of ligand binding, proteins were dialyzed overnight in 25 mm Hepes (pH 7.5), 100 mm NaCl, 5 mm ??-mercaptoethanol, and 5% g...More data for this Ligand-Target Pair
Activity Spreadsheet -- ITC Data from BindingDB
Found 9 hits for monomerid = 50308984
ITC DataΔG°: -8.12kcal/mole −TΔS°: 9.93kcal/mole ΔH°: -9.79kcal/mole
pH: 7.5 T: 4.00°C
pH: 7.5 T: 4.00°C
ITC DataΔG°: -7.88kcal/mole −TΔS°: 1.20kcal/mole ΔH°: -9.08kcal/mole
pH: 7.5 T: 5.00°C
pH: 7.5 T: 5.00°C
ITC DataΔG°: -7.88kcal/mole −TΔS°: 4.06kcal/mole ΔH°: -12.0kcal/mole
pH: 7.5 T: 10.00°C
pH: 7.5 T: 10.00°C
ITC DataΔG°: -7.88kcal/mole −TΔS°: 6.68kcal/mole ΔH°: -14.6kcal/mole
pH: 7.5 T: 15.00°C
pH: 7.5 T: 15.00°C
ITC DataΔG°: -7.88kcal/mole −TΔS°: 9.80kcal/mole ΔH°: -17.7kcal/mole
pH: 7.5 T: 20.00°C
pH: 7.5 T: 20.00°C
ITC DataΔG°: -7.64kcal/mole −TΔS°: 11.5kcal/mole ΔH°: -19.2kcal/mole
pH: 7.5 T: 25.00°C
pH: 7.5 T: 25.00°C
ITC DataΔG°: -7.40kcal/mole −TΔS°: 7.94kcal/mole ΔH°: -15.2kcal/mole
pH: 7.5 T: 4.00°C
pH: 7.5 T: 4.00°C
ITC DataΔG°: -7.64kcal/mole −TΔS°: 8.61kcal/mole ΔH°: -15.9kcal/mole
pH: 7.5 T: 4.00°C
pH: 7.5 T: 4.00°C
ITC DataΔG°: -7.88kcal/mole −TΔS°: 9.93kcal/mole ΔH°: -17.8kcal/mole
pH: 7.5 T: 4.00°C
pH: 7.5 T: 4.00°C